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Phenotype MicroArrays for Microbial Cells

Fully Automated Omnilog PM-M System

Supplied By: Biolog, USA

Phenotype MicroArrays for mammalian Cells

Fully Automated Omnilog Phenotype MicroArray System for Mammalian Cells

The Biolog OmniLog® simultaneously incubates and monitors 50 microplates with thousands of phenotypic assays to measur e ph ysiolo gical resp on ses in diverse mammalian cells.


Phenotype MicroArrays for Mammalian Cells SystemsPhenotype MicroArrays for Mammalian Cells Systems


The PM-M system includes: instrument, computer, LCD flat panel monitor, software for data collection and analysis, 8 & 12 channel electronic pipettors, user guide, training and one year warranty. Consumables and other accessories are purchased separately.


Omnilog PM System Specifications

Parameter Specification
Size: 530 mm x 810 mm x 580 mm
Power: 100 to 240 volts, 50 to 60 Hz
Operating Temp Range: 18° to 28°C
Operating Humidity Range: 20% to 80% non-condensing
Incubation Temperature Range: 20° to 45°C
Temp Consistency: ± 2°C in the Tray Chamber
Incubation Humidity Range: Ambient
Test Capacity: 50 Micro Plates
Data Capture: CCD images of each microplate at regular intervals
Temperature Control: Input of set temperature by external computer
Temperature Indication: Output to external computer and 7 segment display
Monitor: LCD flat panel, 17 in viewable image size

Buying Guide

All OmniLog PM Systems include the OmniLog incubator/reader, computer, OmniLog PM Software, OmniLog User Guide, Pipettor, Turbidimeter and a one year warranty. Databases are sold separately


Catalog # Description
96161 OmniLog® PM System: The OmniLog PM-M system has the capacity to incubate and monitor up to 50 PM-M MicroPlates for automated cell based metabolic analysis

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Phenotype MicroArray Applications

Phenotype MicroArray Technology is now available for applications with nearly all important cell lines.


General Areas Emphasizing Metabolism

    • Obesity

    • Diabetes

    • Metabolic Disorders

    • Nutrition

    • Aging

    • Mitochondrial Diseases

    • Cancer (Warburg Effect)

    • Chemosensitivity

    • Mitochondrial Toxicity

    • Cellular Toxicity

    • Stem Cell Metabolism

    • Bioprocess Optimization

    • Cell Line QC

    • Cell Energetics

Kinetic Data Capture and Analysis

OmniLog PM-M soware contains a suite of algorithms that work in conjunction with the OmniLog PM-M system and Phenotype MicroArray panels to automate incubation of up to 50 microplates at a user-specified temperature with continuous collection of colorimetric assay data over time. PM-M data analysis programs allow for display of kinetic data, manage and analyze the data, export it in a variety of raw and processed forms, and generate reports.


Phenotype MicroArrays for Mammalian Cells

Software Functions:

    • Drives the operation of the OmniLog PM-M system

    • Guides loading and reading of plates or PM-M panels

    • Creates a kinetic data file for each P-MM panel

File Management/Kinetic Analysis

    • Assembles plate or PM-M panel data files into data lists

    • Displays kinetic plots of the data

    • Allows export of kinetic plots as bmp or jpeg files

Parametric Analysis:

    • Extracts data lists from the File Management /Kinetic Analysis module

    • Calculates parameters from kinetic data

    • Allows comparison of two data lists

    • Highlights wells and generates a report on phenotypes that differ significantly in any selected kinetic analysis parameter

    • Allows identification of substrates in all PM-M panels

    • Links metabolic substrates in PM-M panels to KEGG database

    • Exports the original OmniLog kinetic data

    • Export data parameters for statistical & bio-informatic analysis

Phenotype MicroArrays for Mammalian Cells SystemsPhenotype MicroArrays for Mammalian Cells Systems


OmniLog-PM’s PMM Assay Portfolio

    • Carbon Energy & Nitrogen Substrates: 367 metabolic substrates. Substrates include carbohydrates/starches, alcohols, fatty acids, ketones, carboxylic acids, amino acids and dipeptides on 4x96 well microplates

    • Hormones: 45 different hormones each at six different concentrations on 3x96 well microplates

    • Trace Elements: 22 different ions/cofactors each at four different concentrations on 1x96 well microplate

    • Anti-Cancer Chemosensitivity: 92 anti-cancer agents each at four different concentrations on 4x96 well microplates

    • Mitochondrial Toxicity: 8 carbon-energy substrates (associated with diverse pathways, e.g. hexose, pentose, etc.) to distinguish different aspects of mitochondrial activity/dysregulation in the context of chemical/drug screens on 1x96 well microplate

Phenotype MicroArrays for Mammalian Cells

Phenotype MicroArrays for Mammalian Cells

 

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